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  • Home
  • Technical Info
    • About
    • Illustrative Overview
    • FAQ
    • Perils of Hyperventilation
  • Our Story
    • Our Story
    • News & Press Releases
    • Contributors
    • Donate
  • Contact Us
    • Contact Us
    • Meet The Team
    • Visit FirePencil LLC
  • Endorsements
    • Endorsements
    • Supporters
    • Endorse Us


​The Perils of Hyperventilation


​More is not better! 
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​
Higher respiratory rates and/or excessive volumes during manual resuscitation result in the increased likelihood of morbidity and mortality.  Studies indicate that hyperventilation is happening at alarming rates and frequencies both inside and outside of hospital settings.  The longer the period of hyperventilation, the more likely the patient is to experience related complications such as...
1. Decreased likelihood of survival
2. Cerebral hypoxia resulting in a corresponding decrease in the chances of baseline neurological outcome and increased chances of permanent neurological damage
3. Reduced cardiac output and blood pressure
4. Gastric inflation resulting in emesis, aspiration and subsequent pneumonia
5. Lung damage

Learn more from the links below.
​

References

Aufderheide, T. & Lurie, K. (2004) Death by hyperventilaion: A common and life threatening problem during cardiopulmonary resuscitation. Journal of Critical Care Medicine. Retrieved from https://www.researchgate.net/publication/8207887_Death_by_hyperventilation_A_common_and_life-threatening_problem_during_cardiopulmonary_resuscitation

Aufderheide, T., Gardar, S., Pirrallo, R., Yannopoulos, D., McKnite, S., Briesen, C., Sparks, C., Conrad, C., Provo, T., & Lurie, K. (2004) Hyperventilation-Induced Hypotension During Cardiopulmonary Resuscitation.
American Heart Assocation Journal. Retrieved from http://circ.ahajournals.org/content/109/16/1960

Abella, B., Alvarado, J., Myklebust, H., Edelson, D., Barry, A., O'Hearn, N, Vanden Hoek, T., & Becker, L. (2005) Quality of Cardiopulmonary Resuscitation During In-Hospital Cardiac Arrest. The Journal of the American Medicine Association. Retrieved from http://jama.jamanetwork.com/article.aspx?articleid=200195

Han, M. et al. (2011). Short Women With Severe Sepsis-Related Acute Lung Injury Receive Lung Protective Ventilation Less Frequently: An Observational Cohort Study. Critical Care.  Retrieved from http://ccforum.biomedcentral.com/articles/10.1186/cc10524​

Hasegawa, K. et al. (2013) Association of Prehospital Advanced Airway Management with Neurologic Outcome and Survival in Patients with Out-of-Hospital Cardiac Arrest.  The Journal of American Medical Association, (309), 3.  Retrieved from http://jama.jamanetwork.com/article.aspx?articleid=1557712

Kohler, K., Losert, H., Sterz, F., et al., (2006) Quality of Cardio Pulmonary Resuscitation Among Highly Trained Staff in an Emergency Department Setting.  Arch Intern Med, 166: 2375–80.  
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http://archinte.jamanetwork.com/article.aspx?articleid=411316

Link, M., Berkow, L., Kudenchuk, P., Halperin, H., Hess, E., Moitia, V., Neuman, R., O'Neil, B., Paxton, J., Silvers, S., White, R., Yannopoulos, D., & Donnino, M. (2015). American Heart Association Guidelines Update for Cadiopulmonary Resuscitation and Emergency Cardiovascular Care. American Heart Association Adult Advanced Cardiovascular Life Support. Retrieved from http://circ.ahajournals.org/content/132/18_suppl_2/S444.full


McInnes, A., Sutton, R., Orioles, A., Nishisaki, A., Niles, D., Abella, B., Maltese, M. & Berg, R. (2011) The First Quantitative Report of Ventilation Rate During Resuscitation of Older Children and Adolescents.  Resuscitation, 82(8). Retrieved from 
www.sciencedirect.com/science/article/pii/S0300957211002139

Milander, M., Hiscok, P., Sanders, A., Kern, K., Berg, R. & Ewy, G. (1995) Chest Compression and Ventilation Rates During Cardiopulmonary Resuscitation: The Effects of Audible Tone Guidance. Academic Emergency Medicine, 2(8).  Retrieved from www.ncbi.nlm.nih.gov/pubmed/7584749

Mondolfi, A., Bachur, R., Grenier, B., & Thompson, J. (1997) Comparison of Self-Inflating Bags with Anesthesia Bags for Bag-Mask Ventilation in the Pediatric Emergency Department. Pediatric Emergency Care. 13(5).  Retrieved from 
http://www.ncbi.nlm.nih.gov/pubmed/9368241

Niebauer, J., White M., Zinkan J., Youngblood A. & Tofil N. (2011) Hyperventilation in Pediatric Resuscitation: Performance in Simulated Pediatric Medical Emergencies. Retrieved from
 http://pediatrics.aappublications.org/content/128/5/e1195

O'Neill, J. & Deakin, C. (2007). Do we hyperventilate cardiac arrest patients? Resuscitation. DOI 10.1016/j.resuscitation.2006.09.01. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17289248?dopt=Abstract

Weiler, N., Heinrichs, W. & Dick, W. (1995) Assessment of Pulmonary Mechanics and Gastric Inflation Pressure During Mask Ventilation. Prehospital Disaster Medicine, 10(2). Retrieved from ​http://www.ncbi.nlm.nih.gov/pubmed/10155411?dopt=Abstract
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